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24/01/2019 - Science and Technology

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January 24, 2019

Despite creating a revolution in medical sciences, Gene editing technology in humans has its own limitations. Analyze (200 Words)

Refer - The Hindu

Enrich the answer from other sources, if the question demands.

 

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IAS Parliament 5 years

KEY POINTS

Gene editing, a revolution

·        A group of scientists at UC San Diego used CRISPR to make a population of mosquitoes resistant to spreading malaria.

·        Scientists used CRISPR to identify the set of essential genes a human cancer cell needs to survive.

·        Scientists are already using gene editing to treat diseases in people, a form of gene therapy. By tweaking special cells in body's immune system, they were able to send them on a search-and-destroy mission to target cancerous tumor cells.

Limitations

·        Deactivating a gene in two human embryos, which means that the changes he made could be inherited by the next generation.

·        In doing so, this violates the widely held ethical consensus that it is too early for germline editing, for we simply don’t know enough yet about the risks of such experiments.

·        Studies have shown that the technology can result in unintended mutations, which in turn can cause cancers.

·        Every gene likely influences multiple traits, depending on the environment it interacts with. This makes it hard to predict the ultimate outcome of an embryo-editing exercise without decades of follow-up.

Predictability of risks, consequences of experiments conducted should be comprehensively documented with appropriate scientific explanations. Without this experimenting with human embryos violates the ethical conduct.

Sandeep 5 years

Kindly review

IAS Parliament 5 years

Good answer. Keep Writing.

Rahul 5 years

Pls review

IAS Parliament 5 years

Good answer. Keep Writing

Qurat 5 years

Please review

IAS Parliament 5 years

Avoid lengthy introduction. Otherwise a good answer. Keep Writing.

Ashita jain 5 years

Plz review...

IAS Parliament 5 years

Introductions are not mandatory. Use it only when it is necessary. Good answer. Keep Writing.

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