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Poultry Driven Anti-Microbial Resistance

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February 01, 2018

What is the issue?

  • Last-hope antibiotics like “colistin” are being used indiscriminately by the Indian poultry industry to enhance chicken weight.
  • This is leading to increased drug resistance and is presently completely legal as regulations are very lax in this domain.  

What is Colistin?

  • Medicines and antibiotics are given to the birds to protect them from diseases or to make them gain weight faster, to enhance productivity.
  • One drug typically given this way is “Colistin”, which is used to treat patients critically ill with infections that have become resistant to multiple drugs.
  • As such drugs are critical to humans, WHO has called restricting their use for animal treatment and demanded a ban on using them as growth promoters.
  • Their continued use in farming as growth enhancers increases the chances of development of bacterial resistance and will render them useless to patients.
  • The Market - Yet, about 2800 tonnes of veterinary colistin were shipped to countries, including - Vietnam, India, South Korea and Russia, in 2016.
  • The total is likely to be higher as the product may be shipped under its brand name rather than being labelled outright as colistin.
  • Notably, India imports more than 150 tonnes of colistin along with some local production, but U.K. uses less than a tonne a year of colistin in agriculture.
  • Lax Regulations - In India, at least five animal pharmaceutical companies are openly advertising products containing colistin as growth promoters.
  • Companies selling them argue that their products are therapeutic in nature although mild doses can be used at a preventive level (which increases weight).
  • While most sellers claim that they don’t encourage indiscriminate use, branded colistin is easily procurable in India, without even a prescription.
  • This is completely legal as there is no regulation like in Europe, where colistin can be accessed only on a prescribed by a vet for the treatment of sick animals.

What is the science behind?

  • A colistin-resistant gene was discovered in Chinese pigs in 2015.
  • This gene (mcr-1) was found to be transferable within and between bacterial species, which implies that microbes could just acquire from elsewhere.
  • This is a lot easier and faster way to develop resistance than developing resistance individually, which will complicate disease combat efforts.
  • The spread - Colistin-resistance is contaminating the meat, spreading on the chicken farms, in the surrounding air, to the farm workers and flies etc...
  • Significantly, mcr variants have already been detected in bacteria from animals and humans in more than 30 countries, spanning four continents.
  • These revelations have created worldwide panic in the medical community as many multi-drug resistant strands have become very prominent lately.
  • The consequence - Drug resistence is a big threat to global health, food security, and development and makes multiple drugs ineffective.
  • It renders medical practitioners with no treatment options.
  • Currently, the problem is thought to kill 0.7 million people annually worldwide, which is expected to rise to 10 million by 2050 if no action is taken.
  • Also, common procedures like joint replacements, Caesarean sections, organ transplants and chemotherapy could also become too risky to carry out.
  • The Solution - Calistin should be thought of and treated as an environmental toxin and its export world over as chicken feed, needs to be curtailed.
  • Notably, some have even vouched for a worldwide ban on not just colistin but all antibiotics as growth promoters.

How does the Indian scenario fare?

  • Drug Resistance - India is the epicentre of the global drug resistance crisis, due to a combination of factors conducive for superbug development.
  • Unregulated sale of drugs for both human and animal use, unsanitary practices, burgeoning population, and improper drains are a few to name.
  • Significantly, some of the pharmaceutical companies have also been found to be following substandard sewage treatment practices for their drug excretes.
  • Poultrty Sector - As it is religiously neutral, chicken meat is the favoured non-veg dish in India and the local poultry industry is booming.
  • Produced has doubled between 2003 and 2013 and majority of poultry is now produced by commercial farms, that are contracted to major companies.
  • Meat from supermarkets in the country has been found to contained residues of six antibiotics, suggesting they were being used liberally on farms.
  • Experts predict the rising demand for protein will enhance demand for chicken, which will consequently also see enhanced antibiotics in the food.  
  • Notably, the main problem is with the mass medicating of livestock with antibiotics as preventives, which the WHO has already sought to ban.

What is the way forward?

  • Using antibiotics as growth promoters has already been banned in the EU and U.S. in 2017 and India too needs to follow suit immediately.
  • “National Action Plan on Anti-Microbial Resistance” in 2017, did ban the using antibiotics as growth promoters, but no follow up regulatiory action has come.  
  • Notably, it has been observed that Indian farmers use antibiotics as a substitute for maintaining nutritious and hygienic growth environments.  
  • While the reason for such attitudes is the perception that such an approach is chaper than the cost of maintainance, which is actually not correct. 
  • Apart from mere regulations, as consumer pressure and awareness holds key to drive in a large scale change in, the masses need to be made aware.

 

Source: The Hindu

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